Nonfunctioning Juxtaglomerular Cell Tumor
نویسندگان
چکیده
The juxtaglomerular cell tumor (JGCT) is a rare renal tumor characterized by excessive renin secretion causing intractable hypertension and hypokalemia. However, asymptomatic nonfunctioning JGCT is extremely rare. Here, we report a case of nonfunctioning JGCT in a 31-year-old woman. The patient presented with a left renal tumor without hypertension or hypokalemia. Under a clinical diagnosis of renal cell carcinoma, radical nephrectomy was performed. The tumor was located in the middle portion adjacent to the renal pelvis, measuring 2 cm in size. Pathologically, the tumor was composed of cuboidal cells forming a solid arrangement, immunohistochemically positive for renin. Based on these findings, the tumor was diagnosed as JGCT. In cases with hyperreninism, preoperative diagnosis of JGCT is straightforward but difficult in nonfunctioning case. Generally, JGCT presents a benign biological behavior. Therefore, we should take nonfunctioning JGCT into the differential diagnoses for renal tumors, especially in younger patients to avoid excessive surgery.
منابع مشابه
[Juxtaglomerular cell tumor: a case report].
We report a case of juxtaglomerular cell tumor. A 17-year-old female complained of headache with severe hypertension, hypokalemia, and elevated level of plasma renin activity. Computerized tomographic (CT) scan revealed a slightly enhanced tumor at middle pole of right kidney. Angiography showed a hypovascular tumor. A renin secreting tumor of the right kidney was diagnosed and right nephrectom...
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Juxtaglomerular cell tumor (JGCT) generally affects adolescents and young adults. The patients experience symptoms related to hypertension and hypokalemia due to renin-secretion by the tumor. Grossly, the tumor is well circumscribed with fibrous capsule and the cut surface shows yellow or gray-tan color with frequent hemorrhage. Histologically, the tumor is composed of monotonous polygonal cell...
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Treatment of juxtaglomerular cell tumor of the kidney by retroperitoneal laparoscopic partial nephrectomy.
INTRODUCTION Juxtaglomerular cell tumor (JCT) of the kidney, first described by Robertson and colleagues in 1967,(1) is a rare cause of serve hypertension. Because the tumor is small, mainly occurs in children and young adults, and has benign nature, nephron-sparing surgery is particularly recommended.(2) Here we present for the first time a case of JCT in a 29-year old woman who underwent retr...
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عنوان ژورنال:
دوره 2013 شماره
صفحات -
تاریخ انتشار 2013